Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention (ERIC-PPCI)
A multicentre randomised controlled clinical trial.
Aim: To determine whether remote ischaemic conditioning (RIC) improves clinical outcomes in STEMI patients undergoing PPCI.
Primary Endpoint: To investigate whether RIC reduces the combined primary endpoint rate of cardiac death and hospitalisation for heart failure (HHF) at 12 months in STEMI patients undergoing PPCI.
To investigate whether RIC can affect the following secondary endpoints below:
- Rates of cardiac death and HHF at 30 days. This data will be collected at the clinical follow up outpatient
appointment (at 6-8 weeks post-PPCI).
- Rates of all-cause death, repeat coronary revascularisation, reinfarction, stroke at 30 days and 12 months.
This data will be collected at the clinical follow up outpatient appointment (at 6-8 weeks and one year
- TIMI flow post PPCI28
- Quality of life at 6-8 weeks and 12 months (EuroQol EQ-5D-5L)